Downregulation of sorting nexin 10 is associated with overexpression of miR-30d during liver cancer progression in rats
نویسندگان
چکیده
منابع مشابه
the study of aaag repeat polymorphism in promoter of errg gene and its association with the risk of breast cancer in isfahan region
چکیده: سرطان پستان دومین عامل مرگ مرتبط با سرطان در خانم ها است. از آنجا که سرطان پستان یک تومور وابسته به هورمون است، می تواند توسط وضعیت هورمون های استروئیدی شامل استروژن و پروژسترون تنظیم شود. استروژن نقش مهمی در توسعه و پیشرفت سرطان پستان ایفا می کند و تاثیر خود را روی بیان ژن های هدف از طریق گیرنده های استروژن اعمال می کند. اما گروه دیگری از گیرنده های هسته ای به نام گیرنده های مرتبط به ا...
15 صفحه اولThe Progression of Liver Fibrosis Is Related with Overexpression of the miR-199 and 200 Families
BACKGROUND Chronic hepatitis C (CH) can develop into liver cirrhosis (LC) and hepatocellular carcinoma (HCC). Liver fibrosis and HCC development are strongly correlated, but there is no effective treatment against fibrosis because the critical mechanism of progression of liver fibrosis is not fully understood. microRNAs (miRNAs) are now essential to the molecular mechanisms of several biologica...
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BACKGROUND This study aimed to assess the role of RNA-dependent adenosine deaminase (ADAR1) in cervical squamous cell carcinoma occurrence and progression. METHODS ADAR1 expression levels in stage IA and stage IIA cervical squamous cell carcinoma (group A), cervical intraepithelial neoplasia (CIN) specimens (group B), as well as normal and inflamed cervical tissue samples (group C) were asses...
متن کاملmiR-519d-mediated downregulation of STAT3 suppresses breast cancer progression.
MicroRNAs (miRNAs) play important roles in the the gene regulation of carcinogenesis including breast cancer. miR‑519d has been studied in various types of cancer, but its role in breast cancer remains unclear. In the present study, we investigated the expression and biological function of miR-519d in breast cancer. Using quantitative RT-PCR (RT-qPCR) analysis, we analyzed the expression of miR...
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Accumulating evidence suggested that microRNA (miRNA) plays an important role in the carcinogenesis of bladder cancer. MicroRNA-138-5p (miR-138-5p) was dysregulated in human cancers including bladder cancer. However, its clinical significance remains unclear. We recruited 126 patients with bladder cancer in the study. Real-time quantitative polymerase chain reaction (RT-qPCR) was conducted for ...
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ژورنال
عنوان ژورنال: Tumor Biology
سال: 2017
ISSN: 1010-4283,1423-0380
DOI: 10.1177/1010428317695932